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Synthesis of C(3)-symmetric star-shaped molecules containing α-amino acids and dipeptides via Negishi coupling as a key step

We demonstrate a new synthetic strategy toward star-shaped C(3)-symmetric molecules containing α-amino acid (AAA) derivatives and dipeptides. In this regard, trimerization and Negishi cross-coupling reactions are used as the key steps starting from readily available 4’-iodoacetophenone and L-serine....

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Kotha, Sambasivarao, Todeti, Saidulu
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369998/
https://ncbi.nlm.nih.gov/pubmed/30800186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.33
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