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Identification of CDC42 Effectors Operating in FGD1-Dependent Trafficking at the Golgi

Loss of function mutations in the FGD1 gene cause a rare X-linked disease, faciogenital dysplasia (FGDY, also known as Aarskog-Skott syndrome), which is associated with bone and urogenital abnormalities. The FGD1 gene encodes à CDC42-specific guanine nucleotide exchange factor. The mutations are fre...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Egorov, Mikhail, Polishchuk, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369352/
https://ncbi.nlm.nih.gov/pubmed/30778386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00007
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