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The toxin from a ParDE toxin‐antitoxin system found in Pseudomonas aeruginosa offers protection to cells challenged with anti‐gyrase antibiotics

Toxin‐antitoxin systems are mediators of diverse activities in bacterial physiology. For the ParE‐type toxins, their reported role of gyrase inhibition utilized during plasmid‐segregation killing indicates they are toxic. However, their location throughout chromosomes leads to questions about functi...

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Bibliographic Details
Published in:Mol Microbiol
Main Authors: Muthuramalingam, Meenakumari, White, John C., Murphy, Tamiko, Ames, Jessica R., Bourne, Christina R.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368863/
https://ncbi.nlm.nih.gov/pubmed/30427086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14165
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