Atorvastatin Protects Against Cerebral Aneurysmal Degenerative Pathology by Promoting Endothelial Progenitor Cells (EPC) Mobilization and Attenuating Vascular Deterioration in a Rat Model

BACKGROUND: Endothelial injury is the early pathological change of cerebral aneurysm (CA) formation. In addition to its lipid-lowering activity, atorvastatin (ATR) also reportedly promotes vascular repair via mobilizing endothelial progenitor cells (EPC). Here, we investigated the influence of ATR o...

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Vydáno v:Med Sci Monit
Hlavní autoři: Wei, Huijie, Yang, Mengchen, Yu, Kai, Dong, Wang, Liang, Wang, Wang, Zengguang, Jiang, Rongcai, Zhang, Jianning
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Animal Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368826/
https://ncbi.nlm.nih.gov/pubmed/30710072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915005
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