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Positive response to Icotinib in metastatic lung adenocarcinoma with acquiring EGFR Leu792H mutation after AZD9291 treatment: a case report

BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have been emerged as the standard selection in non-small cell lung cancer (NSCLC) patients with EGFR sensitive mutations. However, primary or acquired resistance to EGFR-TKIs seems inevitable, especially to third-gen...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Wang, Junhui, Chen, Jianxin
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368759/
https://ncbi.nlm.nih.gov/pubmed/30736738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5352-7
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