Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis

In this work, the hydrophobic small molecule NF-κB inhibitor celastrol was loaded into poly(ethylene glycol)-b-poly(propylene sulfide) (PEG-b-PPS) micelles. PEG-b-PPS micelles demonstrated high loading efficiency, low polydispersity, and no morphological changes upon loading with celastrol. Encapsul...

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Bibliografiske detaljer
Udgivet i:Biomater Sci
Main Authors: Allen, Sean D., Liu, Yu-Gang, Kim, Taehyeung, Bobbala, Sharan, Yi, Sijia, Zhang, Xiaohan, Choi, Jaehyuk, Scotta, Evan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368678/
https://ncbi.nlm.nih.gov/pubmed/30601470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8bm01224e
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