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A recombinant vesicular stomatitis-based Lassa fever vaccine elicits rapid and long-term protection from lethal Lassa virus infection in guinea pigs

The World Health Organization has identified Lassa virus (LASV) as one of the top five pathogens to cause a severe outbreak in the near future. This study assesses the ability of a leading vaccine candidate, recombinant Vesicular stomatitis virus expressing LASV glycoprotein (VSVΔG/LASVGPC), and its...

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Bibliografiske detaljer
Udgivet i:NPJ Vaccines
Main Authors: Stein, Derek R., Warner, Bryce M., Soule, Geoff, Tierney, Kevin, Frost, Kathy L., Booth, Stephanie, Safronetz, David
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368541/
https://ncbi.nlm.nih.gov/pubmed/30774999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0104-x
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