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Chemical Screening Using Cell-Free Xenopus Egg Extract

Most drug screening methods use purified proteins, cultured cells, and/or small model organisms such as Xenopus, zebrafish, flies, or nematodes. These systems have proven successes in drug discovery, but they also have weaknesses. Although purified cellular components allow for identification of com...

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Bibliographic Details
Published in:Cold Spring Harb Protoc
Main Authors: Broadus, Matthew R., Lee, Ethan
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368528/
https://ncbi.nlm.nih.gov/pubmed/29475996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot098277
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