Analysis of DNA Methylation at Specific Loci in Stool Samples Detects Colorectal Cancer and High-Grade Dysplasia in Patients With Inflammatory Bowel Disease

BACKGROUND & AIMS: Patients with inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn’s disease, are at increased risk for colorectal cancer (CRC). Analyses of DNA methylation patterns in stool samples have been reported to detect CRC in patients with IBD. We sought to vali...

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Publicat a:Clin Gastroenterol Hepatol
Autors principals: Kisiel, John B., Klepp, Pasquale, Allawi, Hatim T., Taylor, William R., Giakoumopoulos, Maria, Sander, Tamara, Yab, Tracy C., Moum, Bjorn A., Lidgard, Graham P., Brackmann, Stephan, Mahoney, Douglas W., Roseth, Arne, Ahlquist, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368476/
https://ncbi.nlm.nih.gov/pubmed/29775793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2018.05.004
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