Analysis of DNA Methylation at Specific Loci in Stool Samples Detects Colorectal Cancer and High-Grade Dysplasia in Patients With Inflammatory Bowel Disease

BACKGROUND & AIMS: Patients with inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn’s disease, are at increased risk for colorectal cancer (CRC). Analyses of DNA methylation patterns in stool samples have been reported to detect CRC in patients with IBD. We sought to vali...

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Detalhes bibliográficos
Publicado no:Clin Gastroenterol Hepatol
Main Authors: Kisiel, John B., Klepp, Pasquale, Allawi, Hatim T., Taylor, William R., Giakoumopoulos, Maria, Sander, Tamara, Yab, Tracy C., Moum, Bjorn A., Lidgard, Graham P., Brackmann, Stephan, Mahoney, Douglas W., Roseth, Arne, Ahlquist, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368476/
https://ncbi.nlm.nih.gov/pubmed/29775793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2018.05.004
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