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The NHR1-1 of Prs1 and the pentameric motif (284)KKCPK(288) of Prs3 permit multi-functionality of the PRPP synthetase in Saccharomyces cerevisiae

The five-membered PRS gene family of Saccharomyces cerevisiae is an example of gene duplication allowing the acquisition of novel functions. Each of the five Prs polypeptides is theoretically capable of synthesising PRPP but at least one of the following heterodimers is required for survival: Prs1/P...

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Bibliografske podrobnosti
izdano v:FEMS Yeast Res
Main Authors: Sauvaget, Maëlle, Hutton, Fraser, Coull, Robert, Vavassori, Stefano, Wang, Ke, Reznik, Aleksandra, Chyker, Tatsiana, Newfield, Chelsea G, Euston, Eloise, Benary, Gerrit, Schweizer, Lilian M, Schweizer, Michael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368438/
https://ncbi.nlm.nih.gov/pubmed/30649305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsyr/foz006
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