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Development of novel lipidic particles for siRNA delivery that are highly effective after 12 months storage

Liposomes are versatile and well-proven as a means to deliver nucleic acids into cells. Most of the formulation procedures used are labour intensive and result in unstable end products. We have previously reported on the development of a simple, yet efficient, hydration-of-freeze-dried-matrix (HFDM)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Clarke, Daniel, Idris, Adi, McMillan, Nigel A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368384/
https://ncbi.nlm.nih.gov/pubmed/30735545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211954
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