Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM

c-di-AMP is an important second messenger molecule that plays a pivotal role in regulating fundamental cellular processes, including osmotic and cell wall homeostasis in many Gram-positive organisms. In the opportunistic human pathogen Staphylococcus aureus, c-di-AMP is produced by the membrane-anch...

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Udgivet i:PLoS Pathog
Main Authors: Tosi, Tommaso, Hoshiga, Fumiya, Millership, Charlotte, Singh, Rahul, Eldrid, Charles, Patin, Delphine, Mengin-Lecreulx, Dominique, Thalassinos, Konstantinos, Freemont, Paul, Gründling, Angelika
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368335/
https://ncbi.nlm.nih.gov/pubmed/30668586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007537
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