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First trimester placental endothelial cells from pregnancies with abnormal uterine artery Doppler are more sensitive to apoptotic stimuli

Failure of the placental capillary network to develop normally is associated with early onset fetal growth restriction (FGR) and pre-eclampsia (PE). Although the symptoms are observed at term, the problem begins in the first trimester. However, investigations at this clinically relevant time are hin...

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Bibliographic Details
Published in:Lab Invest
Main Authors: Charolidi, Nicoletta, Host, Amanda J., Ashton, Sandra, Tryfonos, Zoe, Leslie, Karin, Thilaganathan, Baskaran, Cartwright, Judith E., Whitley, Guy S.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group US 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368249/
https://ncbi.nlm.nih.gov/pubmed/30291324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0139-z
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