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In situ imaging of aminopeptidase N activity in hepatocellular carcinoma: a migration model for tumour using an activatable two-photon NIR fluorescent probe

CD13/aminopeptidase N (APN), which is a zinc-dependent metalloproteinase, plays a vital role in the growth, migration, angiogenesis, and metastasis of tumours. Thus, in situ molecular imaging of endogenous APN levels is considerably significant for investigating APN and its different functions. In t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Li, Haidong, Li, Yueqing, Yao, Qichao, Fan, Jiangli, Sun, Wen, Long, Saran, Shao, Kun, Du, Jianjun, Wang, Jingyun, Peng, Xiaojun
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368242/
https://ncbi.nlm.nih.gov/pubmed/30842824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04685a
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