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In situ imaging of aminopeptidase N activity in hepatocellular carcinoma: a migration model for tumour using an activatable two-photon NIR fluorescent probe

CD13/aminopeptidase N (APN), which is a zinc-dependent metalloproteinase, plays a vital role in the growth, migration, angiogenesis, and metastasis of tumours. Thus, in situ molecular imaging of endogenous APN levels is considerably significant for investigating APN and its different functions. In t...

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Vydáno v:Chem Sci
Hlavní autoři: Li, Haidong, Li, Yueqing, Yao, Qichao, Fan, Jiangli, Sun, Wen, Long, Saran, Shao, Kun, Du, Jianjun, Wang, Jingyun, Peng, Xiaojun
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368242/
https://ncbi.nlm.nih.gov/pubmed/30842824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04685a
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