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Feasibility of dose escalation using intraoperative radiotherapy following resection of large brain metastases compared to postoperative stereotactic radiosurgery

BACKGROUND AND PURPOSE: Post-operative SRS (stereotactic radiosurgery) for large brain metastases is challenged by risks of radiation necrosis that limit SRS dose. Intraoperative radiotherapy (IORT) is a potential alternative, however standard dose recommendations are lacking. METHODS AND MATERIALS:...

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Publicat a:J Neurooncol
Autors principals: Vargo, John A., Sparks, Kristie M., Singh, Rahul, Jacobson, Geraldine M., Hack, Joshua D., Cifarelli, Christopher P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368183/
https://ncbi.nlm.nih.gov/pubmed/30094718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-018-2968-4
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