Host mRNA decay proteins influence HIV-1 replication and viral gene expression in primary monocyte-derived macrophages

BACKGROUND: Mammalian cells harbour RNA quality control and degradative machineries such as nonsense-mediated mRNA decay that target cellular mRNAs for clearance from the cell to avoid aberrant gene expression. The role of the host mRNA decay pathways in macrophages in the context of human immunodef...

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Dades bibliogràfiques
Publicat a:Retrovirology
Autors principals: Rao, Shringar, Amorim, Raquel, Niu, Meijuan, Breton, Yann, Tremblay, Michel J., Mouland, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367771/
https://ncbi.nlm.nih.gov/pubmed/30732620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0465-2
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