Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania

BACKGROUND: Tuberculosis (TB) is the leading cause of death from an infectious disease and the roll-out of rapid molecular diagnostics for rifampin resistance has resulted in a steady rise in the number of patients with multidrug-resistant (MDR)-TB referred for treatment. Pyrazinamide is used in sus...

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Veröffentlicht in:BMC Infect Dis
Hauptverfasser: Juma, Saumu Pazia, Maro, Athanasia, Pholwat, Suporn, Mpagama, Stellah G., Gratz, Jean, Liyoyo, Alphonse, Houpt, Eric R., Kibiki, Gibson S., Mmbaga, Blandina T., Heysell, Scott K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367741/
https://ncbi.nlm.nih.gov/pubmed/30732572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-019-3757-1
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