18β-glycyrrhetyl-3-O-sulfate would be a causative agent of licorice-induced pseudoaldosteronism

Licorice-induced pseudoaldosteronism is a common adverse effect in traditional Japanese Kampo medicine, and 3-monoglucuronyl glycyrrhetinic acid (3MGA) was considered as a causative agent of it. Previously, we found 22α-hydroxy-18β-glycyrrhetyl-3-O-sulfate-30-glucuronide (1), one of the metabolites...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ishiuchi, Kan’ichiro, Morinaga, Osamu, Ohkita, Takeshi, Tian, Chuanting, Hirasawa, Asuka, Mitamura, Miaki, Maki, Yasuhito, Kondo, Tsubasa, Yasujima, Tomoya, Yuasa, Hiroaki, Minamizawa, Kiyoshi, Namiki, Takao, Makino, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367500/
https://ncbi.nlm.nih.gov/pubmed/30733510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38182-2
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