Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort

Renal transplant recipients have an increased risk of non-melanoma skin cancer (NMSC) compared to in the general population. Here, we show polygenic risk scores (PRS) calculated from genomewide association studies (GWAS) of NMSC in general, non-transplant setting, can predict risk of, and time to po...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Stapleton, Caragh P., Birdwell, Kelly A., McKnight, Amy Jayne, Maxwell, Alexander P., Mark, Patrick B., Sanders, M. Lee, Chapman, Fiona A., van Setten, Jessica, Phelan, Paul J., Kennedy, Claire, Jardine, Alan, Traynor, Jamie P., Keating, Brendan, Conlon, Peter J., Cavalleri, Gianpiero L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367067/
https://ncbi.nlm.nih.gov/pubmed/30085400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15057
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