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FTO affects hippocampal function by regulation of BDNF processing
Initially, the function of the fat mass and obesity associated (Fto) gene seemed to be primarily the regulation of the body weight. Here we show that loss of Fto results in a hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis. In consequence, Fto(-/-) mice display an anxiety-like behav...
Gespeichert in:
| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366932/ https://ncbi.nlm.nih.gov/pubmed/30730976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211937 |
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