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Rpd3L Contributes to the DNA Damage Sensitivity of Saccharomyces cerevisiae Checkpoint Mutants

DNA replication forks that are stalled by DNA damage activate an S-phase checkpoint that prevents irreversible fork arrest and cell death. The increased cell death caused by DNA damage in budding yeast cells lacking the Rad53 checkpoint protein kinase is partially suppressed by deletion of the EXO1...

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Bibliografske podrobnosti
izdano v:Genetics
Main Authors: Gómez-González, Belén, Patel, Harshil, Early, Anne, Diffley, John F. X.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366903/
https://ncbi.nlm.nih.gov/pubmed/30559326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301817
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