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The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype

BACKGROUND: The codon 72 polymorphism in the p53 gene relates to the risk of breast cancer (BC), but this relationship in racially diverse populations is not known. The present study examined the prognostic value of this polymorphism for African American (AA) and Caucasian (CA) BC patients separatel...

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Publicat a:PLoS One
Autors principals: Hebert-Magee, Shantel, Yu, Han, Behring, Michael, Jadhav, Trafina, Shanmugam, Chandrakumar, Frost, Andra, Eltoum, Isam-Eldin, Varambally, Sooryanarayana, Manne, Upender
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366783/
https://ncbi.nlm.nih.gov/pubmed/30730944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211734
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