Improved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children’s Oncology Group AALL0434 Methotrexate Randomization

PURPOSE: Early intensification with methotrexate (MTX) is a key component of acute lymphoblastic leukemia (ALL) therapy. Two different approaches to MTX intensification exist but had not been compared in T-cell ALL (T-ALL): the Children’s Oncology Group (COG) escalating dose intravenous MTX without...

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Publicat a:J Clin Oncol
Autors principals: Winter, Stuart S., Dunsmore, Kimberly P., Devidas, Meenakshi, Wood, Brent L., Esiashvili, Natia, Chen, Zhiguo, Eisenberg, Nancy, Briegel, Nikki, Hayashi, Robert J., Gastier-Foster, Julie M., Carroll, Andrew J., Heerema, Nyla A., Asselin, Barbara L., Gaynon, Paul S., Borowitz, Michael J., Loh, Mignon L., Rabin, Karen R., Raetz, Elizabeth A., Zweidler-Mckay, Patrick A., Winick, Naomi J., Carroll, William L., Hunger, Stephen P.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2018
Matèries:
ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366301/
https://ncbi.nlm.nih.gov/pubmed/30138085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2018.77.7250
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