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Long non-coding RNA LINC00346 promotes pancreatic cancer growth and gemcitabine resistance by sponging miR-188-3p to derepress BRD4 expression

BACKGROUND: Long non-coding RNA LINC00346 has been recently suggested as a prognostic marker in pancreatic cancer. However, its biological function in pancreatic cancer has not yet been determined. In this study, we attempted to ascertain the role of LINC00346 in regulating the aggressiveness of pan...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Shi, Weidong, Zhang, Chenyue, Ning, Zhouyu, Hua, Yongqiang, Li, Ye, Chen, Lianyu, Liu, Luming, Chen, Zhen, Meng, Zhiqiang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366022/
https://ncbi.nlm.nih.gov/pubmed/30728036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1055-9
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