Oxidative Pathways of Deoxyribose and Deoxyribonate Catabolism

Using genome-wide mutant fitness assays in diverse bacteria, we identified novel oxidative pathways for the catabolism of 2-deoxy-d-ribose and 2-deoxy-d-ribonate. We propose that deoxyribose is oxidized to deoxyribonate, oxidized to ketodeoxyribonate, and cleaved to acetyl coenzyme A (acetyl-CoA) an...

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Udgivet i:mSystems
Main Authors: Price, Morgan N., Ray, Jayashree, Iavarone, Anthony T., Carlson, Hans K., Ryan, Elizabeth M., Malmstrom, Rex R., Arkin, Adam P., Deutschbauer, Adam M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365646/
https://ncbi.nlm.nih.gov/pubmed/30746495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00297-18
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