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Functional cardiac orexin receptors: role of orexin-B/orexin 2 receptor in myocardial protection

Orexins/hypocretins exert cardiovascular effects which are centrally mediated. In the present study, we tested whether orexins and their receptors may also act in an autocrine/paracrine manner in the heart exerting direct effects. Quantitative reverse transcription-PCR (RT-PCR), immunohistochemical...

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Bibliographic Details
Published in:Clin Sci (Lond)
Main Authors: Patel, Vanlata H., Karteris, Emmanouil, Chen, Jing, Kyrou, Ioannis, Mattu, Harman S., Dimitriadis, Georgios K., Rodrigo, Glenn, Antoniades, Charalambos, Antonopoulos, Alexios, Tan, Bee K., Hillhouse, Edward W., Ng, Andre, Randeva, Harpal S.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365625/
https://ncbi.nlm.nih.gov/pubmed/30467191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20180150
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