Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood–brain barrier permeability in the corpus callosum

Murine chronic cerebral hypoperfusion (CCH) results in white matter (WM) injury and behavioral deficits. Pericytes influence blood–brain barrier (BBB) integrity and cerebral blood flow. Under hypoxic conditions, pericytes detach from perivascular locations increasing vessel permeability and neuronal...

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Vydáno v:J Cereb Blood Flow Metab
Hlavní autoři: Liu, Qinghai, Radwanski, Ryan, Babadjouni, Robin, Patel, Arati, Hodis, Drew M, Baumbacher, Peter, Zhao, Zhen, Zlokovic, Berislav, Mack, William J
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2017
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365610/
https://ncbi.nlm.nih.gov/pubmed/29192539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17743670
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