Experimental chronic cerebral hypoperfusion results in decreased pericyte coverage and increased blood–brain barrier permeability in the corpus callosum

Murine chronic cerebral hypoperfusion (CCH) results in white matter (WM) injury and behavioral deficits. Pericytes influence blood–brain barrier (BBB) integrity and cerebral blood flow. Under hypoxic conditions, pericytes detach from perivascular locations increasing vessel permeability and neuronal...

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Bibliografske podrobnosti
izdano v:J Cereb Blood Flow Metab
Main Authors: Liu, Qinghai, Radwanski, Ryan, Babadjouni, Robin, Patel, Arati, Hodis, Drew M, Baumbacher, Peter, Zhao, Zhen, Zlokovic, Berislav, Mack, William J
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365610/
https://ncbi.nlm.nih.gov/pubmed/29192539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17743670
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