Genome-wide profiling of human papillomavirus DNA integration in liquid-based cytology specimens from a Gabonese female population using HPV capture technology

Human papillomavirus (HPV) is recognised as the cause of precancerous and cancerous cervical lesions. Furthermore, in high-grade lesions, HPV is frequently integrated in the host cell genome and associated with the partial or complete loss of the E1 and E2 genes, which regulate the activity of viral...

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Опубликовано в: :Sci Rep
Главные авторы: Nkili-Meyong, Andriniaina Andy, Moussavou-Boundzanga, Pamela, Labouba, Ingrid, Koumakpayi, Ismaël Hervé, Jeannot, Emmanuelle, Descorps-Declère, Stéphane, Sastre-Garau, Xavier, Leroy, Eric M., Belembaogo, Ernest, Berthet, Nicolas
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365579/
https://ncbi.nlm.nih.gov/pubmed/30728408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37871-2
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