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Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis

Eupatorin has been reported with in vitro cytotoxic effect on several human cancer cells. However, reports on the mode of action and detail mechanism of eupatorin in vitro in breast cancer disease are limited. Hence, eupatorin’s effect on the human breast carcinoma cell line MCF-7 and MDA-MB-231 was...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Razak, Nursyamirah Abd, Abu, Nadiah, Ho, Wan Yong, Zamberi, Nur Rizi, Tan, Sheau Wei, Alitheen, Noorjahan Banu, Long, Kamariah, Yeap, Swee Keong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365513/
https://ncbi.nlm.nih.gov/pubmed/30728391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37796-w
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