A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity

Photosensitivity, or skin sensitivity to ultraviolet radiation (UVR), is a feature of lupus erythematosus and other autoimmune and dermatologic conditions, but the mechanistic underpinnings are poorly understood. Here, we identify a Langerhans cell (LC)-keratinocyte axis that limits UVR-induced kera...

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Bibliografiska uppgifter
I publikationen:Sci Transl Med
Huvudupphovsmän: Shipman, William D., Chyou, Susan, Ramanathan, Anusha, Izmirly, Peter M., Sharma, Sneh, Pannellini, Tania, Dasoveanu, Dragos C., Qing, Xiaoping, Magro, Cynthia M., Granstein, Richard D., Lowes, Michelle A., Parmer, Eric G., Kaplan, Daniel H., Salmon, Jane E., Mehrara, Babak J., Young, James W., Clancy, Robert M., Blobel, Carl P., Lu, Theresa T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365282/
https://ncbi.nlm.nih.gov/pubmed/30111646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aap9527
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