The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice

Schizophrenia (SCZ) is a devastating mental disorder with poorly defined underlying molecular mechanisms. The gut microbiome can modulate brain function and behaviors through the microbiota-gut-brain axis. Here, we found that unmedicated and medicated patients with SCZ had a decreased microbiome α-d...

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Pubblicato in:Sci Adv
Autori principali: Zheng, Peng, Zeng, Benhua, Liu, Meiling, Chen, Jianjun, Pan, Junxi, Han, Yu, Liu, Yiyun, Cheng, Ke, Zhou, Chanjuan, Wang, Haiyang, Zhou, Xinyu, Gui, Siwen, Perry, Seth W., Wong, Ma-Li, Licinio, Julio, Wei, Hong, Xie, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365110/
https://ncbi.nlm.nih.gov/pubmed/30775438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau8317
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