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Rapamycin-induced miR-30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Vascular senescence is considered to be an independent risk factor for cardiovascular diseases. The present study aimed to investigate the effects of rapamycin on miR-30a and its relationship with autophagy and senescence in vascular smooth muscle cells (VSMCs). Young and aging VSMCs were treated wi...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Tan, Pan, Wang, Haiqin, Zhan, Junkun, Ma, Xinyu, Cui, Xingjun, Wang, Yanjiao, Wang, Yi, Zhong, Jiayu, Liu, Youshuo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365076/
https://ncbi.nlm.nih.gov/pubmed/30747228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4074
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