Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness

BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive de...

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Gepubliceerd in:N Engl J Med
Hoofdauteurs: Girard, T.D., Exline, M.C., Carson, S.S., Hough, C.L., Rock, P., Gong, M.N., Douglas, I.S., Malhotra, A., Owens, R.L., Feinstein, D.J., Khan, B., Pisani, M.A., Hyzy, R.C., Schmidt, G.A., Schweickert, W.D., Hite, R.D., Bowton, D.L., Masica, A.L., Thompson, J.L., Chandrasekhar, R., Pun, B.T., Strength, C., Boehm, L.M., Jackson, J.C., Pandharipande, P.P., Brummel, N.E., Hughes, C.G., Patel, M.B., Stollings, J.L., Bernard, G.R., Dittus, R.S., Ely, E.W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364999/
https://ncbi.nlm.nih.gov/pubmed/30346242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1808217
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