Influenza-induced immune suppression to methicillin-resistant Staphylococcus aureus is mediated by TLR9

Bacterial lung infections, particularly with methicillin-resistant Staphylococcus aureus (MRSA), increase mortality following influenza infection, but the mechanisms remain unclear. Here we show that expression of TLR9, a microbial DNA sensor, is increased in murine lung macrophages, dendritic cells...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Martínez-Colón, Giovanny J., Warheit-Niemi, Helen, Gurczynski, Stephen J., Taylor, Quincy M., Wilke, Carol A., Podsiad, Amy B., Crespo, Joel, Bhan, Urvashi, Moore, Bethany B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364947/
https://ncbi.nlm.nih.gov/pubmed/30682165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007560
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