Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies

BACKGROUND: A cationic liposome-PEG-PEI complex (LPPC) was employed as a carrier for achieving targeted delivery of drug to human epidermal growth factor receptor-2 (HER2/neu)-expressing breast cancer cells. LPPC can be easily loaded with an anti-tumor drug and non-covalently associated with an anti...

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Udgivet i:J Nanobiotechnology
Main Authors: Lin, Yu-Ling, Tsai, Nu-Man, Chen, Chia-Hung, Liu, Yen-Ku, Lee, Chung-Jen, Chan, Yi-Lin, Wang, Yu-Shan, Chang, Yuan-Ching, Lin, Chi-Hsin, Huang, Tse-Hung, Wang, Chao Ching, Chi, Kwan-Hwa, Liao, Kuang-Wen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364477/
https://ncbi.nlm.nih.gov/pubmed/30728015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-019-0457-3
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