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A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers
A supramolecular peptide vaccine system was designed in which epitope-bearing peptides self-assemble into elongated nanofibers composed almost entirely of alpha-helical structure. The nanofibers were readily internalized by antigen presenting cells and produced robust antibody, CD4+ T-cell, and CD8+...
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| Publicado no: | ACS Biomater Sci Eng |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364304/ https://ncbi.nlm.nih.gov/pubmed/30740520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.7b00561 |
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