Existing Host Range Mutations Constrain Further Emergence of RNA Viruses

RNA viruses are capable of rapid host shifting, typically due to a point mutation that confers expanded host range. As additional point mutations are necessary for further expansions, epistasis among host range mutations can potentially affect the mutational neighborhood and frequency of niche expan...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Zhao, Lele, Seth-Pasricha, Mansha, Stemate, Dragoş, Crespo-Bellido, Alvin, Gagnon, Jacqueline, Draghi, Jeremy, Duffy, Siobain
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
Onderwerpen:
Genetic Diversity and Evolution
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364021/
https://ncbi.nlm.nih.gov/pubmed/30463962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01385-18
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