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Efficient Inhibition of Avian and Seasonal Influenza A Viruses by a Virus-Specific Dicer-Substrate Small Interfering RNA Swarm in Human Monocyte-Derived Macrophages and Dendritic Cells

Influenza A viruses (IAVs) are viral pathogens that cause epidemics and occasional pandemics of significant mortality. The generation of efficacious vaccines and antiviral drugs remains a challenge due to the rapid appearance of new influenza virus types and antigenic variants. Consequently, novel s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Jiang, Miao, Österlund, Pamela, Westenius, Veera, Guo, Deyin, Poranen, Minna M., Bamford, Dennis H., Julkunen, Ilkka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364019/
https://ncbi.nlm.nih.gov/pubmed/30463970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01916-18
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