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The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation

Beyond their role in cellular RNA metabolism, DExD/H-box RNA helicases are hijacked by various RNA viruses in order to assist replication of the viral genome. Here, we identify the DExH-box RNA helicase 9 (DHX9) as a binding partner of chikungunya virus (CHIKV) nsP3 mainly interacting with the C-ter...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Matkovic, Roy, Bernard, Eric, Fontanel, Simon, Eldin, Patrick, Chazal, Nathalie, Hassan Hersi, Deka, Merits, Andres, Péloponèse, Jean-Marie, Briant, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364007/
https://ncbi.nlm.nih.gov/pubmed/30463980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01764-18
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