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Prediction of Optimal Drug Schedules for Controlling Autophagy

The effects of molecularly targeted drug perturbations on cellular activities and fates are difficult to predict using intuition alone because of the complex behaviors of cellular regulatory networks. An approach to overcoming this problem is to develop mathematical models for predicting drug effect...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Shirin, Afroza, Klickstein, Isaac S., Feng, Song, Lin, Yen Ting, Hlavacek, William S., Sorrentino, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363771/
https://ncbi.nlm.nih.gov/pubmed/30723233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38763-9
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