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Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli
Osteoarthritis (OA) is a degenerative condition caused by dysregulation of multiple molecular signalling pathways. Such dysregulation results in damage to cartilage, a smooth and protective tissue that enables low friction articulation of synovial joints. Matrix metalloproteinases (MMPs), especially...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6363221/ https://ncbi.nlm.nih.gov/pubmed/30677026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006685 |
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