Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids

Disruption of intestinal barrier homeostasis is an important pathogenic factor in conditions such as irritable bowel syndrome (IBS). Lactobacillus rhamnosus GG (LGG) improves IBS symptoms through unclear mechanisms. Previous studies utilizing colorectal adenocarcinoma cell lines showed that LGG meta...

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Bibliographic Details
Published in:Gut Microbes
Main Authors: Han, Xu, Lee, Allen, Huang, Sha, Gao, Jun, Spence, Jason R., Owyang, Chung
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Research Paper/Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363076/
https://ncbi.nlm.nih.gov/pubmed/30040527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2018.1479625
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