Behavioral remodeling of normal and cancerous epithelial cell lines with differing invasion potential induced by substrate elastic modulus

The micro-environment of cancer cells in the body is mechanically stiffer than that of normal cells. We cultured three breast cell lines of MCF10A-normal, MCF7-noninvasive, and MDA-MB-231-invasive on PDMS substrates with different elastic moduli and different cellular features were examined.Effects...

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Vydáno v:Cell Adh Migr
Hlavní autoři: Ansardamavandi, Arian, Tafazzoli-Shadpour, Mohammad, Shokrgozar, Mohammad Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363025/
https://ncbi.nlm.nih.gov/pubmed/29969940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2018.1475803
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