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Decrease in invasion of HTR-8/SVneo trophoblastic cells by interferon gamma involves cross-communication of STAT1 and BATF2 that regulates the expression of JUN

Trophoblast invasion is one of the critical steps during embryo implantation. IFNG secreted during pregnancy by uterine NK cells acts as a negative regulator of invasion. IFNG in a dose dependent fashion inhibits invasion of HTR-8/SVneo trophoblastic cells. It phosphorylates STAT1 both at tyr 701 an...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Verma, Sonam, Pal, Rahul, Gupta, Satish Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363024/
https://ncbi.nlm.nih.gov/pubmed/29394132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2018.1434030
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