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Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism

The transcriptional factor Nrf2, a master regulator of oxidative stress and inflammation that are tightly linked to the development and progression of cerebral ischemia pathology, plays a vital role in inducing the endogenous neuroprotective process. Here, hypoxic-ischemia (HI) was performed in adul...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Liu, Lei, Vollmer, Mary K., Ahmad, Abdullah S., Fernandez, Victoria M., Kim, Hocheol, Doré, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362849/
https://ncbi.nlm.nih.gov/pubmed/30458277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.11.017
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