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Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood–Brain Barrier Disruption after Ischemic Stroke

Ischemic stroke destroys blood–brain barrier (BBB) integrity. There are currently no effective treatments available in the clinical setting. Post-ischemia treatment with phenothiazine drugs [combined chlorpromazine and promethazine (C+P)] has been shown to be neuroprotective in stroke. The present s...

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Publicat a:Cell Transplant
Autors principals: Li, Fengwu, Geng, Xiaokun, Yip, James, Ding, Yuchuan
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362522/
https://ncbi.nlm.nih.gov/pubmed/30569751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689718819443
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