The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability

Metazoans contain two homologs of the Gcn5-binding protein Ada2, Ada2a and Ada2b, which nucleate formation of the ATAC and SAGA complexes, respectively. In Drosophila melanogaster, there are two splice isoforms of Ada2b: Ada2b-PA and Ada2b-PB. Here, we show that only the Ada2b-PB isoform is in SAGA;...

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Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Torres-Zelada, Eliana F., Stephenson, Robert E., Alpsoy, Aktan, Anderson, Benjamin D., Swanson, Selene K., Florens, Laurence, Dykhuizen, Emily C., Washburn, Michael P., Weake, Vikki M.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362396/
https://ncbi.nlm.nih.gov/pubmed/30559249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.214072
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