AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC

Telomerase reverse transcriptase (TERT) and telomerase RNA component (TERC) constitute the core telomerase enzyme that maintains the length of telomeres. Telomere maintenance is affected in a broad range of cancer and degenerative disorders. Taking advantage of gain‐ and loss‐of‐function approaches,...

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Vydáno v:EMBO Rep
Hlavní autoři: Laudadio, Ilaria, Orso, Francesca, Azzalin, Gianluca, Calabrò, Carlo, Berardinelli, Francesco, Coluzzi, Elisa, Gioiosa, Silvia, Taverna, Daniela, Sgura, Antonella, Carissimi, Claudia, Fulci, Valerio
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362350/
https://ncbi.nlm.nih.gov/pubmed/30591524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201845969
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