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Evolution-guided evaluation of the inverted terminal repeats of the synthetic transposon Sleeping Beauty

Sleeping Beauty (SB) is a synthetic Tc1/mariner transposon that is widely used for genetic engineering in vertebrates, including humans. Its sequence was derived from a consensus of sequences found in fish species including the Atlantic salmon (Salmo salar). One of the functional components of SB, t...

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Pubblicato in:Sci Rep
Autori principali: Scheuermann, Barbara, Diem, Tanja, Ivics, Zoltán, Andrade-Navarro, Miguel A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362248/
https://ncbi.nlm.nih.gov/pubmed/30718656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38061-w
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