Do polygenic risk and stressful life events predict pharmacological treatment response in obsessive compulsive disorder? A gene–environment interaction approach

The rate of response to pharmacological treatment in Obsessive-compulsive disorder (OCD) oscillates between 40 and 70%. Genetic and environmental factors have been associated with treatment response in OCD. This study analyzes the predictive ability of a polygenic risk score (PRS) built from OCD-ris...

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Detaylı Bibliyografya
Yayımlandı:Transl Psychiatry
Asıl Yazarlar: Alemany-Navarro, María, Costas, Javier, Real, Eva, Segalàs, Cinto, Bertolín, Sara, Domènech, Laura, Rabionet, Raquel, Carracedo, Ángel, Menchón, Jose M., Alonso, Pino
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362161/
https://ncbi.nlm.nih.gov/pubmed/30718812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0410-0
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